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How Cheminformatics Has Been Changed by Machine Learning? – Recent Progress
How Cheminformatics Has Been Changed by Machine Learning?
8月 6
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PRISM Biolab
7月 2026
Fast Click Chemistry: Overview of Reaction Rates and Its Meaning
Click chemistry combines two characteristic substituents in a fast and high yielding manner under mild conditions.
7月 31
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PRISM Biolab
Global Reactivity Model for Synthesis for Industrial Applications
Industrial and commercial synthesis is necessary step to go through in process chemistry.
7月 9
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PRISM Biolab
6月 2026
Free Concentrations and Drug Concentration Asymmetry in Plasma and Tissues
Free drug theory (FDT) is like a dogma for the analysis of in vivo pharmacokinetics and pharmacodynamics (PK/PD).1),2),3),4),5) Drug-like small…
6月 30
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PRISM Biolab
Insights from Evaluation of AI-driven Drug Discovery Until 2023 in Clinical Trials
Application of artificial intelligence (AI) in drug discovery and development is a worldwide trend in this era.
6月 12
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PRISM Biolab
5月 2026
Prostate Cancer and Radiopharmaceuticals of 177Lu, 225Ac and 213Bi
Prostate-specific membrane antigen (PSMA) is a promising target to achieve a selective delivery to prostate cancer.1) Even though its significance in…
5月 28
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PRISM Biolab
Hit to Lead in silico: Difference from Lead Optimization and AILDE Approach
Hit to lead is an essential stage for the discovery of drug leads of definite properties with high probability of expanding the chemical and PK/PD…
5月 16
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PRISM Biolab
Condensation Reagents for Peptide/Amide Bonds: Still Under Development
This post is related to chemistry issues related to peptide/amide bond formation.
5月 1
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PRISM Biolab
4月 2026
Conformational Selection or Induced Fit? Complexity of Macromolecule Interactions
Complexation of a protein and the ligand induces biological functions and hence its control is the key for drug discovery.
4月 15
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PRISM Biolab
Current State of in silico Target fishing
Drug discovery commences with careful selection of a target related to diseases.
4月 1
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PRISM Biolab
3月 2026
Chemical Synthesis Paradigm Shift from Intuition to Unmanned System
Chemical synthesis has long been fully dependent on intuition of talented chemists.
3月 18
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PRISM Biolab
2月 2026
Structure Database and Dynamics: Insight from Analysis of Cambridge Structural Database
Application of big data in science database stimulates our mind to give rise to a novel idea for scientific discovery.
2月 27
•
PRISM Biolab
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